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Grade C

Clume Health review

Written by Elena Voss, Metabolic Health Editor

Elena Voss is a mother writing for mothers, not a treating clinician, and holds no medical license. Prices and terms come from the company's own published pages. This is background reading, not medical advice.

It names four dispensing pharmacies outright and tells you who prescribes, which almost nothing else on this list does, and it charges the same price whichever molecule you pick — $259 a month on the full-dose Signature program and $219 on the maintenance and microdosing one, semaglutide or tirzepatide, oral or injectable. For anyone who wants the dual agonist that is worth real money, since most sellers here add $80 to $150 a month for it. The pricing you meet first is the problem. Clume's homepage advertises programs starting at $199 and $159 a month, nothing on the site is priced at either figure, and the asterisks beside both lead to no footnote anywhere on the page. The cheaper rates it does publish are prepaid terms rather than monthly bills: $186 a month means committing 52 weeks, and $200 means twelve. Canceling needs 72 hours' notice before the next billing date or that cycle is charged anyway, and no refund is given for the month you cancel or any month before it.

$259/mo
Flat price · every dose
Consult Medication
See plans at Clume Health
  • Confirm HSA / FSA coverage
  • Public information reviewed
  • Confirm your total cost
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Clume Health at a glance

Semaglutide
$259/mo
Tirzepatide
$259/mo
Coverage
Not published
Brand-name
Compounded only

How we scored Clume Health

Every factor comes from Clume Health's own published pricing, disclosures and oversight, and the six combine into the 39/100 Metabolic-Fit Score on our weighted six-factor framework. Commissions don't change a provider's score.

Postpartum & breastfeeding guidance20/100 · Weak

No postpartum or breastfeeding framing — a generic weight program.

PCOS & hormonal fit28/100 · Weak

Thin on the hormonal picture that drives many mothers' weight.

Clinical oversight & labs62/100 · Weak

Oversight and lab support fall short of the best on our list — the review below says exactly where.

True monthly cost38/100 · Weak

Cost is unpredictable or sits at the premium end.

Ongoing support55/100 · Weak

Support is thin once the prescription ships.

Cancellation fairness30/100 · Weak

Exit terms are the weak point: lock-in, notice periods, or a cancellation you have to chase.

How we checked this review

Names four dispensing pharmacies outright, which almost no compounded seller does, and charges the same whichever molecule you choose — $259 a month on the full-dose program, $219 on the maintenance and microdosing one, semaglutide or tirzepatide, oral or injectable. The pricing you see first is not the pricing you can buy. Its homepage advertises programs starting at $199 and $159 a month and nothing on the site costs either figure, with asterisks that lead to no footnote at all. The cheaper rates it does publish are prepaid terms: $186 a month means committing a full 52 weeks. Canceling needs 72 hours' notice or you are billed for that cycle, and no month is refunded.

Pricing

MedicationPricePlan
Compounded semaglutide$259Signature program, full dose, month-to-monthThe rate you can actually pay month to month. The $186 figure advertised alongside it requires prepaying a 52-week term.
Compounded tirzepatide$259Signature program, full dose, month-to-monthIdentical to semaglutide — Clume prices by program rather than by molecule, so the dual agonist costs no more.
Compounded semaglutide$219Microdose/Maintain program, month-to-monthThe maintenance and microdosing track. Its cheaper $200 rate requires a 12-week prepaid term.
Compounded tirzepatide$219Microdose/Maintain program, month-to-monthAgain the same price as semaglutide on the same program.

Swipe the table to see plan details →

Many HSA and FSA plans cover GLP-1 telehealth — check yours. These figures are what Clume Health's own site disclosed at last review; this market re-prices often, so confirm the current number at the source.

What we like

  • Names four dispensing pharmacies outright, which most compounded sellers never do
  • Names OpenLoop as the prescribing layer rather than leaving the clinical relationship vague
  • The same price for semaglutide or tirzepatide, oral or injectable — the molecule does not change the bill
  • Offers a separate maintenance and microdosing program at a lower rate
  • Names its operating company, North Atelier LLC, in its own terms

The caveats

  • The homepage advertises "starting at *$199/month" and "*$159/month" and no program costs either
  • Those asterisks lead to no footnote anywhere on the page
  • The cheapest advertised rates require prepaying a full term — $186/mo means 52 weeks
  • Canceling needs 72 hours' notice before the next billing date or that cycle is charged
  • No refund for the month in which you cancel, or for any prior month
  • No state list is published, and nothing addresses pregnancy, breastfeeding or postpartum timing

The program determines the price

Clume Health lists its full-dose Signature program from $259 per month and its Microdose/Maintain program from $219. Each program offers semaglutide or tirzepatide, oral or injectable, at the same listed program price. That makes the actual clinical category important: the lower maintenance or microdose amount is not simply a discount on an identical Signature prescription. Ask the clinician which preparation is proposed and why, then obtain the supply and complete charge for that specific choice.

Lower advertised equivalents require longer prepayment: $186 on a 52-week Signature plan and $200 on a twelve-week Microdose/Maintain plan. Those terms should remain attached to the smaller figures. Ask for the actual amount collected and how the service defines its monthly equivalent within a week-based commitment. Do not assume that a 52-week total is twelve times a label without the agreement confirming the calculation. The full financial authorization matters more than a smaller number presented for comparison.

The homepage does not match the program menu

The homepage advertises weight-management programs starting at $199 and a molecular-optimization offer from $159, with asterisks that do not lead to an explanatory footnote. Those figures do not match the published program choices. Request a written explanation instead of treating either as a hidden cheaper GLP-1 plan. The molecular program also concerns products such as NAD+ and sermorelin, which are separate from the semaglutide and tirzepatide purchase under consideration.

A wide program menu can support a useful clinical conversation without making every offering appropriate or necessary. Keep any adjunct itemized with its own clinical rationale and charge. Likewise, equal prices for oral and injected forms do not establish equal evidence, interchangeable dosing, or identical administration instructions. Compounded oral preparations should not inherit an approved brand's labeling. A patient should receive a product-specific explanation rather than choose a route simply because the storefront makes the monthly amount the same.

The clinical layer and seller are identified

The legal material names North Atelier LLC doing business as Clume Health, while OpenLoop provides the clinical and prescribing layer. Clume also names four dispensing pharmacies. Those disclosures are useful for understanding responsibility, but confirm the actual practice, clinician, and licensed pharmacy location assigned to your prescription. A partner list does not establish that every order has the same concentration, ingredients, or instructions, and a shared pharmacy does not by itself prove common ownership with another brand.

The service does not publish a complete state list. Confirm eligibility where you will attend care and receive medication before starting an application. For a compounded product, request the formulation, quantity, storage, usable period, and written directions. Compounded medications are not FDA approved. A named clinical network or pharmacy improves accountability without transferring an approved brand's regulatory status to the finished preparation or establishing specialist expertise in every medical circumstance.

Seventy-two hours is the stopping deadline

Clume requires cancellation at least 72 hours before the next billing date to avoid that cycle's charge. Its policy states that the month of cancellation and prior months are not refunded. Those limits matter more when choosing a longer financial term, and the agreement should explain how they apply to an unused prepaid balance. Obtain the actual cancellation method and confirmation rather than rely only on the ability to contact customer support when another order is approaching.

Clume may interest someone who values named care partners and wants several forms under one program structure. The mismatched homepage figures and week-based prepayment need clarification before choosing on the lower equivalent. Its public material does not substantively address pregnancy, breastfeeding, postpartum timing, or PCOS, so relevant needs deserve direct discussion. Compare the actual program, full charge, prescription, accessible follow-up, and stopping terms together. Neither the equal molecule price nor a lower maintenance label should replace an individual clinical and financial assessment.

The bottom line for mothers

Best for: Someone who wants tirzepatide without paying a premium for it, and who cares enough about who compounds the medication to choose a seller that says so.

Alternatives to Clume Health

These are partners — we may be paid if you sign up through these links. The full list has every provider we cover, partner or not.

  • CoreAge RxFeatured partner

    CoreAge's officially linked public offer advertises compounded semaglutide at $79/month and tirzepatide at $129/month across doses, with care and overnight shipping included. It describes one-time purchases without a required subscription. Main navigation still shows semaglutide from $99; confirm your prescription quantity and total, and read the refund limits before paying.

    Visit CoreAge Rx
  • Unusually open about its clinicians and pharmacies — a named CMO, roughly forty-five named physicians, three named compounding pharmacies — and unusually loose about its advertising, having dropped 'comparable to FDA-approved semaglutide' claims only after the National Advertising Division referred it to the FTC.

    Visit Willow
  • Flat pricing through every dose escalation, named partner pharmacies and a state list it actually publishes — undercut by an open FDA warning letter, an F rating at the BBB, and brand-name pens advertised on its site that you cannot buy.

    Visit Sprout Health

Providers like Clume Health

Keep comparing Clume Health

Clume Health, answered

Why does the homepage price not match the programs?
It does not match anything. The homepage advertises GLP-1 and microdose programs "starting at *$199/month" and cellular optimization "starting at *$159/month", and no program on the site is priced at $199 or $159. The asterisks that should explain the gap lead to no footnote anywhere on the page. The real menu starts at $259 for the full-dose program and $219 for maintenance and microdosing.
Does tirzepatide cost more than semaglutide here?
No, and that is genuinely unusual. Clume prices by program rather than by molecule, so $259 buys the full-dose Signature program whether you take semaglutide or tirzepatide, in oral or injectable form. Most sellers on this list charge $80 to $150 more a month for the dual agonist, so anyone who wants tirzepatide should notice this.
What does $186 a month actually require?
A 52-week commitment. The $186 rate on the Signature program and the $200 rate on the Microdose/Maintain program are prepaid terms, not lower monthly bills — 52 weeks and 12 weeks respectively. If you want to keep the option of leaving, the numbers to budget are $259 and $219.
Who prescribes and who compounds?
Clume names both, which is rare. The prescribing layer is OpenLoop — the intake requires agreeing to OpenLoop's telehealth consent and the terms reference OpenLoop Medical Practices — and the terms name four dispensing pharmacies outright rather than describing them as accredited partners. The operating company is North Atelier LLC, trading as Clume Health, under Iowa law.

Pricing, states and verification reflect Clume Health's public disclosures at last review; the Metabolic-Fit Score is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.

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