Metabolic-Fit / 100
Clume Health review
It names four dispensing pharmacies outright and tells you who prescribes, which almost nothing else on this list does, and it charges the same price whichever molecule you pick — $259 a month on the full-dose Signature program and $219 on the maintenance and microdosing one, semaglutide or tirzepatide, oral or injectable. For anyone who wants the dual agonist that is worth real money, since most sellers here add $80 to $150 a month for it. The pricing you meet first is the problem. Clume's homepage advertises programs starting at $199 and $159 a month, nothing on the site is priced at either figure, and the asterisks beside both lead to no footnote anywhere on the page. The cheaper rates it does publish are prepaid terms rather than monthly bills: $186 a month means committing 52 weeks, and $200 means twelve. Canceling needs 72 hours' notice before the next billing date or that cycle is charged anyway, and no refund is given for the month you cancel or any month before it.
- HSA / FSA-eligible
- Editor-vetted
- No insurance needed
Elena Voss is a mother writing for mothers, not a treating clinician, and holds no medical license. Every clinical figure in this piece is cited inline to its primary source — the trial or the FDA label — so you can open it and check us. This is background reading, not medical advice.
Clume Health at a glance
- Semaglutide
- $259/mo
- Tirzepatide
- $259/mo
- Coverage
- Not published
- Brand-name
- Compounded only
How we scored Clume Health
Every factor comes from Clume Health's own published pricing, disclosures and oversight, and the six combine into the 39/100 Metabolic-Fit Score by the same weighted six-factor framework we apply to every provider — never nudged by whether a provider pays us.
No postpartum or breastfeeding framing — a generic weight program.
Thin on the hormonal picture that drives many mothers' weight.
Oversight and lab support fall short of the top of this roster — the review below says exactly where.
Cost is unpredictable or sits at the premium end.
Support is thin once the prescription ships.
Exit terms are the weak point: lock-in, notice periods, or a cancellation you have to chase.
How we verified this review
- Last verified
- September 2026
- Confidence
- medium
- Primary source
- www.clumehealth.com
Names four dispensing pharmacies outright, which almost no compounded seller does, and charges the same whichever molecule you choose — $259 a month on the full-dose program, $219 on the maintenance and microdosing one, semaglutide or tirzepatide, oral or injectable. The pricing you see first is not the pricing you can buy. Its homepage advertises programs starting at $199 and $159 a month and nothing on the site costs either figure, with asterisks that lead to no footnote at all. The cheaper rates it does publish are prepaid terms: $186 a month means committing a full 52 weeks. Canceling needs 72 hours' notice or you are billed for that cycle, and no month is refunded.
Pricing
Prices re-verified
| Medication | Monthly | Plan |
|---|---|---|
| Compounded semaglutide | $259 | Signature program, full dose, month-to-monthThe rate you can actually pay month to month. The $186 figure advertised alongside it requires prepaying a 52-week term. |
| Compounded tirzepatide | $259 | Signature program, full dose, month-to-monthIdentical to semaglutide — Clume prices by program rather than by molecule, so the dual agonist costs no more. |
| Compounded semaglutide | $219 | Microdose/Maintain program, month-to-monthThe maintenance and microdosing track. Its cheaper $200 rate requires a 12-week prepaid term. |
| Compounded tirzepatide | $219 | Microdose/Maintain program, month-to-monthAgain the same price as semaglutide on the same program. |
Swipe the table to see plan details →
Many HSA and FSA plans cover GLP-1 telehealth — check yours. These figures are what Clume Health's own site disclosed at last review; this market re-prices often, so confirm the current number at the source.
What we like
- Names four dispensing pharmacies outright, which most compounded sellers never do
- Names OpenLoop as the prescribing layer rather than leaving the clinical relationship vague
- The same price for semaglutide or tirzepatide, oral or injectable — the molecule does not change the bill
- Offers a separate maintenance and microdosing program at a lower rate
- Names its operating company, North Atelier LLC, in its own terms
The caveats
- The homepage advertises "starting at *$199/month" and "*$159/month" and no program costs either
- Those asterisks lead to no footnote anywhere on the page
- The cheapest advertised rates require prepaying a full term — $186/mo means 52 weeks
- Canceling needs 72 hours' notice before the next billing date or that cycle is charged
- No refund for the month in which you cancel, or for any prior month
- No state list is published, and nothing addresses pregnancy, breastfeeding or postpartum timing
Clume Health for mothers: our verdict
It names four dispensing pharmacies outright and tells you who prescribes, which almost nothing else on this list does, and it charges the same price whichever molecule you pick — $259 a month on the full-dose Signature program and $219 on the maintenance and microdosing one, semaglutide or tirzepatide, oral or injectable. For anyone who wants the dual agonist that is worth real money, since most sellers here add $80 to $150 a month for it. The pricing you meet first is the problem. Clume's homepage advertises programs starting at $199 and $159 a month, nothing on the site is priced at either figure, and the asterisks beside both lead to no footnote anywhere on the page. The cheaper rates it does publish are prepaid terms rather than monthly bills: $186 a month means committing 52 weeks, and $200 means twelve. Canceling needs 72 hours' notice before the next billing date or that cycle is charged anyway, and no refund is given for the month you cancel or any month before it. It runs about $259/month, flat across every dose — a premium to the category, so the extras have to earn it.
We weigh Clume Health the way mothers actually have to: not just the monthly cost, but postpartum and breastfeeding timing and PCOS and insulin resistance — the parts a general weight-loss roundup leaves out.
What Clume Health costs, in full
- Compounded semaglutide — Signature program, full dose, month-to-month: $259/mo
- Compounded tirzepatide — Signature program, full dose, month-to-month: $259/mo
- Compounded semaglutide — Microdose/Maintain program, month-to-month: $219/mo
- Compounded tirzepatide — Microdose/Maintain program, month-to-month: $219/mo
For context, the typical ongoing price across our roster is around $179/month, so Clume Health sits at the premium end.
Clume Health says the price covers the provider visit and the medication. That is the comparison that matters at this price: two providers a few dollars apart can differ by a hundred a month once the extras are counted, so line up what each one bundles before you decide.
The medications Clume Health prescribes
Clume Health prescribes semaglutide and tirzepatide — the two with the largest published weight-loss effects, and carrying both on one account matters when insulin resistance, common with PCOS and after gestational diabetes, makes tirzepatide the better-suited option. These are compounded formulations from a licensed pharmacy — the reason the price stays down — but compounded GLP-1s aren't FDA-approved finished products the way Wegovy and Zepbound are.
A needle-free oral or sublingual option is on the menu, which draws in mothers who've been avoiding injections — just set expectations: oral and buccal delivery of these peptides is far less studied than the injectable versions the trials used.
Where Clume Health fits — and where it doesn't — for mothers
A good fit if…
- switching between semaglutide and tirzepatide may become necessary as your body and your hormones change.
Look elsewhere if…
- you specifically want an FDA-approved brand pen with its own pregnancy and lactation labeling.
- you want frictionless cancellation — read the cancellation and refund terms in the caveats above before you pay.
- you'd rather a prescriber talk through timing around postpartum and breastfeeding timing — that is the ground our #1 pick, CoreAge Rx, is built on.
Oversight, safety, and what we could verify
Our confidence is moderate — the core facts check out, but some details (per-state availability, program mechanics) aren't fully public. As with any compounded GLP-1, the most useful thing mothers can do is confirm which licensed pharmacy fills the prescription and what's in the formulation — we explain how we weigh oversight in our scoring methodology.
One line that applies to every provider on this site: no GLP-1 is established as safe in pregnancy or while breastfeeding, and the labels advise against use. This is a review of a commercial program, not a green light — the timing decision belongs to you and your clinician.
The bottom line
Clume Health is a reasonable option — weigh it on postpartum and breastfeeding timing and PCOS and insulin resistance against the alternatives below. For most mothers, CoreAge Rx remains the stronger all-round fit — see why it tops our ranking.
The bottom line for mothers
Best for: Someone who wants tirzepatide without paying a premium for it, and who cares enough about who compounds the medication to choose a seller that says so.
Alternatives to Clume Health
Providers we have a referral relationship with, ordered by their Metabolic-Fit Score — highest first. This module leaves out the provider whose page you are reading, so on CoreAge Rx's own review our #1 pick is the one name you will not find here. These are not the whole roster: see the full ranking for every provider we cover, paid or not.
- Visit CoreAge Rx92
Metabolic-Fit / 100
CoreAge RxOur #1 pickOne flat price, both molecules on a single chart, and a prescriber who reads your history before writing — the most predictable place for a mother to start and, just as important, to pause.
- Visit Gala Health84
Metabolic-Fit / 100
A flat $179 for either molecule with a genuinely gentle microdosing tier — a reasonable, all-doses-included option if you can live with a yearly plan and a pharmacy it doesn't name.
- Visit Enhance MD81
Metabolic-Fit / 100
One of the more oversight-forward compounded programs here — lab work and a live provider visit bundled into every plan, with a gentle microdosing tier — the catch is that the low '$212' headline you'll see quoted is the 12-month prepay rate, not the $249 you'd pay month to month.
Keep comparing Clume Health
Head-to-head & alternatives
Clume Health, answered
- Why does the homepage price not match the programs?
- It does not match anything. The homepage advertises GLP-1 and microdose programs "starting at *$199/month" and cellular optimization "starting at *$159/month", and no program on the site is priced at $199 or $159. The asterisks that should explain the gap lead to no footnote anywhere on the page. The real menu starts at $259 for the full-dose program and $219 for maintenance and microdosing.
- Does tirzepatide cost more than semaglutide here?
- No, and that is genuinely unusual. Clume prices by program rather than by molecule, so $259 buys the full-dose Signature program whether you take semaglutide or tirzepatide, in oral or injectable form. Most sellers on this list charge $80 to $150 more a month for the dual agonist, so anyone who wants tirzepatide should notice this.
- What does $186 a month actually require?
- A 52-week commitment. The $186 rate on the Signature program and the $200 rate on the Microdose/Maintain program are prepaid terms, not lower monthly bills — 52 weeks and 12 weeks respectively. If you want to keep the option of leaving, the numbers to budget are $259 and $219.
- Who prescribes and who compounds?
- Clume names both, which is rare. The prescribing layer is OpenLoop — the intake requires agreeing to OpenLoop's telehealth consent and the terms reference OpenLoop Medical Practices — and the terms name four dispensing pharmacies outright rather than describing them as accredited partners. The operating company is North Atelier LLC, trading as Clume Health, under Iowa law.
Pricing, states and verification reflect Clume Health's public disclosures at last review; the Metabolic-Fit Score is our editorial judgment per the published methodology. This is background reading, not medical advice — GLP-1 medications are not established as safe in pregnancy or breastfeeding. See our medical disclaimer and how we're funded.