Sesame
Ranked #8 · Grade B−
A real telehealth marketplace with a video visit and a clinician you pick — now brand-first, so you get on-label Wegovy or Zepbound with the manufacturer's own pregnancy labeling, if you can absorb a membership fee stacked on the drug price.
- $25/mo cheaper than Primary Clinic (Direct GLP)
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
One of the few mass-market brands designed around a woman's front door — now selling FDA-approved brand Wegovy and Zepbound instead of the compounded semaglutide it used to, though the posted price is only half the bill once the required $149/mo membership is added.
- $25/mo cheaper than Primary Clinic (Direct GLP)
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
Gala Health
Ranked #4 · Grade B
A flat $179 for either molecule with a genuinely gentle microdosing tier — a reasonable, all-doses-included option if you can live with a yearly plan and a pharmacy it doesn't name.
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
- scores 84/100 against Primary Clinic (Direct GLP)'s 40
ShedRx
Ranked #13 · Grade C
The widest menu on our roster — injections, sublingual lozenges, daily drops, four brand-name pens and the approved oral GLP-1 — with three compounding pharmacies named, a flat price at any dose, and cancellation terms among the most restrictive we have read.
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
SynergyRX
Ranked #14 · Grade C
Now confirmed to publish real GLP-1 prices — compounded semaglutide from $199, tirzepatide from $349, plus brand options — right on its products page, no consult required, contrary to what an earlier check found.
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
Amazon One Medical
Ranked #58 · Grade C
A major, highly recognizable brand — Amazon's own One Medical plus Amazon Pharmacy channel — offering FDA-approved Wegovy from $149/mo with a manufacturer coupon, plus the new oral Foundayo pill, though the $149 price depends on coupon eligibility and there's no postpartum or PCOS-specific content.
- $25/mo cheaper than Primary Clinic (Direct GLP)
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
NovoCare Pharmacy
Ranked #63 · Grade C
The manufacturer's own channel for brand Wegovy — $149/mo self-pay or as low as $25/mo with commercial insurance — but it requires your own existing prescription and offers no tirzepatide, since that's a different company's drug.
- $25/mo cheaper than Primary Clinic (Direct GLP)
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
YourHealthRx
Ranked #49 · Grade C
A science-forward compounded shop with a broad peptide catalog and flat dosing — $170/mo semaglutide, $210/mo tirzepatide ongoing — but the homepage 'as low as' price is a promotional rate, and there's no postpartum or PCOS-specific content.
- $4/mo cheaper than Primary Clinic (Direct GLP)
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- has an oral option if you would rather not inject
CareBareRX
Ranked #18 · Grade C
Both molecules now have confirmed, tiered pricing — found by walking the actual intake, since the public site still carries no price at all — with a real gotcha: the 3-month plan costs more per month than month-to-month.
- serves all 50 states, where Primary Clinic (Direct GLP) lists AZ, CO, DC, FL, GA, IA, ID, KS, MT, NE, NM, NV, NY, OK, OR, UT, VA, WA (18 areas; more coming per its own FAQ)
- offers FDA-approved brand pens, not just compounded
- scores 71/100 against Primary Clinic (Direct GLP)'s 40