Sesame
Ranked #8 · Grade B−
A real telehealth marketplace with a video visit and a clinician you pick — now brand-first, so you get on-label Wegovy or Zepbound with the manufacturer's own pregnancy labeling, if you can absorb a membership fee stacked on the drug price.
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
The most polished route to on-label Wegovy or Zepbound, with a dedicated insurance concierge — powerful if the branded product is the goal, though the membership fee and the medication cost are always two separate charges.
- $46/mo cheaper than Mixx Health & Wellness
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
Gala Health
Ranked #4 · Grade B
A flat $179 for either molecule with a genuinely gentle microdosing tier — a reasonable, all-doses-included option if you can live with a yearly plan and a pharmacy it doesn't name.
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- offers FDA-approved brand pens, not just compounded
- scores 84/100 against Mixx Health & Wellness's 37
ShedRx
Ranked #13 · Grade C
The widest menu on our roster — injections, sublingual lozenges, daily drops, four brand-name pens and the approved oral GLP-1 — with three compounding pharmacies named, a flat price at any dose, and cancellation terms among the most restrictive we have read.
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
SynergyRX
Ranked #14 · Grade C
Now confirmed to publish real GLP-1 prices — compounded semaglutide from $199, tirzepatide from $349, plus brand options — right on its products page, no consult required, contrary to what an earlier check found.
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
One of the few mass-market brands designed around a woman's front door — now selling FDA-approved brand Wegovy and Zepbound instead of the compounded semaglutide it used to, though the posted price is only half the bill once the required $149/mo membership is added.
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- offers FDA-approved brand pens, not just compounded
- has an oral option if you would rather not inject
Belle Health
Ranked #34 · Grade C
Flat-rate pricing with a real dietitian included ($119/mo semaglutide, from $175/mo tirzepatide) from a nine-year-old operator — carrying an open FDA warning letter over how it described its own compounded products.
- $1/mo cheaper than Mixx Health & Wellness
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- scores 52/100 against Mixx Health & Wellness's 37
Trillium Meds
Ranked #49 · Grade C
A straightforward compounded-only shop with real prices for every tier posted on the public site — no intake gate — but the 'Starter Pack' name is a trap if you assume it behaves like the regular 3-month plan.
- $1/mo cheaper than Mixx Health & Wellness
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- scores 50/100 against Mixx Health & Wellness's 37
Cora Health
Ranked #29 · Grade C
The most transparently tiered pricing found in this batch — as low as $99/mo semaglutide or $135/mo tirzepatide on the annual plan, with every tier itemized publicly — from a platform with a thin 36-review Trustpilot count so far.
- $21/mo cheaper than Mixx Health & Wellness
- serves all 50 states, where Mixx Health & Wellness lists 44 states + DC (not AK, AR, MA, NM, OR, RI, SC)
- scores 53/100 against Mixx Health & Wellness's 37